IEEE LaTeX 模板存在问题。当我使用 longtable 环境制作表格时,完成后表格会与相邻的两列格式重叠。
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\begin{longtable}{|l|l|l|l|l|l|}
\caption{The following table summarizing snoRNA expression across cancer types was adapted from Huang et al. (2022):} \label{tab:long} \\
\hline \multicolumn{1}{|c|}{\textbf{snoRNA Name}} & \multicolumn{1}{c|}{\textbf{Cancer Type}} & \multicolumn{1}{c|}{\textbf{Expression}} & \multicolumn{1}{c|}{\textbf{Mechanism, Pathway, or Target}} & \multicolumn{1}{c|}{\textbf{Functions}} & \multicolumn{1}{c|}{\textbf{Reference}}\\ \hline
\endfirsthead
\multicolumn{6}{c}%
{{\bfseries \tablename\ \thetable{} -- continued from previous page}} \\
\hline \multicolumn{1}{|c|}{\textbf{snoRNA Name}} & \multicolumn{1}{c|}{\textbf{Cancer Type}} & \multicolumn{1}{c|}{\textbf{Expression}} & \multicolumn{1}{c|}{\textbf{Mechanism, Pathway, or Target}} & \multicolumn{1}{c|}{\textbf{Functions}} & \multicolumn{1}{c|}{\textbf{Reference}}\\ \hline
\endhead
\hline \multicolumn{6}{|r|}{{Continued on next page}} \\ \hline
\endfoot
\hline \hline
\endlastfoot
SNORA 18L5 & Hepatocellular carcinoma & Up-regulation & p53 & Increase ribosome biogenesis, facilitate ribosomal RNA maturation, and alter the localization of RPL5 and RPL11, allowing for increased MDM2-mediated proteolysis of p53 and cell cycle arrest & \cite{} \\ \hline
SNORA15 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA21 & Colorectal carcinoma & Up-regulation & Unknown & Be involved in epithelial cell differentiation, morphogenesis, and cell adhesion & \cite{} \\ \hline
nan & Gallbladder cancer & Down-regulation & Ecadherin, N-cadherin, vimentin, c-Myc and Cyclin D1 & Inhibit GBC cell migration and invasion by down-regulating the EMT process of GBC cells & \cite{} \\ \hline
nan & Gastric cancer & Up-regulation & Unknown & Be associated with distant metastasis and lymph node metastasis in GC patients & \cite{} \\ \hline
SNORA23 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Pancreatic ductal adenocarcinoma & Up-regulation & SYNE2 & Promote PDAC cell survival and invasion, and growth and metastasis of xenograft tumors through modulation of ribosome biogenesis & \cite{} \\ \hline
SNORA24 & "Colorectal
carcinoma & " Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA26 & Sarcomas & Up-regulation & Rap1, Hippo, MAPK, sphingolipid, TGF-b, Wnt & Enrich in cell differentiation, regulation of cell development, regulation of transcription, cell ecell signaling, and activation of protein kinase B activity & \cite{} \\ \hline
SNORA3 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA31 & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA36B & Head and neck squamous cell carcinoma & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA41 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA42 & Colorectal carcinoma & Up-regulation & Unknown & Increase cell proliferation, tumorigenicity, migration, invasion, and anoikis resistance in colon cancer cells & \cite{} \\ \hline
nan & Lung cancer & Up-regulation & Unknown & Be associated with the expression of stem cell-core transcription factors in lung tumor-initiating cells & \cite{} \\ \hline
nan & Prostate cancer & Up-regulation & Metabolic pathways & Enhance prostate cancer cell viability, migration, and EMT & \cite{} \\ \hline
SNORA47 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA52 & Hepatocellular carcinoma & Down-regulation & Unknown & Function as a potential diagnostic and prognostic marker for HCC & \cite{} \\ \hline
SNORA55 & Prostate cancer & Up-regulation & Unknown & biomarker for HCC patients Be involved in the cell-to-cell signaling and interaction & \cite{} \\ \hline
SNORA6 & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA62 & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA65 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA68 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA70F & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA71A & Breast cancer & Up-regulation & ROCK2, TGF-b & Promote breast tumor growth and enhance metastasis of breast cancer & \cite{} \\ \hline
nan & colorectal carcinoma & Up-regulation & LBP, NF-kappa B, Toll-like receptor & Promote CRC cell migration and invasion & \cite{} \\ \hline
SNORA71B & Breast cancer & Up-regulation & EMT & Promote the proliferation, migration, and invasion of breast cancer cells with different metastatic abilities & \cite{} \\ \hline
SNORA71C & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA73B & Sarcomas & Up-regulation & Oxidative phosphorylation, metabolic pathways, NF-kappaB, stimulatory C-type lectin receptor & Enrich in cell cycle, regulation of protein ubiquitination, and RNA metabolic process & \cite{} \\ \hline
SNORA74A & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA78 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA7A & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORA7B & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD104 & Leukemia & Up-regulation & Unknown & Lead to the disorder of rRNA methylation, and also lead to the decrease of cell volume and the repair speed of damaged protein & \cite{} \\ \hline
SNORD105 & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD105B & Gastric cancer & Up-regulation & ALDOA/C-Myc Pathway & Be associated with tumor size, differentiation, and pathological stage in GC as well as affect proliferation, migration, and invasion in multiple GC cell lines & \cite{} \\ \hline
SNORD110 & Leukemia & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD112-114 & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD113-1 & Hepatocellular carcinoma & Down-regulation & MAPK/ERK, TGF-b & Function as a tumor suppressor role in HCC and be important as a potential diagnostic and therapeutic target for HCC & \cite{} \\ \hline
SNORD114-17 & Head and neck squamous cell carcinoma & Up-regulation & PI3K/AKT, the ECM receptor & Be involved in the regulation of cell adhesion, invasion, and metastasis & \cite{} \\ \hline
SNORD116-18 & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD126 & Hepatocellular carcinoma & Up-regulation & FGFR2, PI3K-AKT & Promote the progression of HCC & \cite{} \\ \hline
SNORD12B & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD12C/SNORD106 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD14E & Colorectal carcinoma & Up-regulation & Unknown & Be involved in systemic lupus erythematosus, alcoholism, viral carcinogenesis, transcriptional mis-regulation in cancer & \cite{} \\ \hline
SNORD15A & Breast cancer & Up-regulation & p53 & Compromise tumorigenicity both in vitro and in vivo via activation of p53 & \cite{} \\ \hline
SNORD15B & Breast cancer & Up-regulation & p53 & Compromise tumorigenicity both in vitro and in vivo via activation of p53 & \cite{} \\ \hline
SNORD17 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Hepatocellular carcinoma & Up-regulation & p53 & Promote the growth and tumorigenicity of HCC cells in vitro and in vivo & \cite{} \\ \hline
SNORD1C & Colorectal carcinoma & Up-regulation & Unknown & Involvement of snoRNAs in the regulation of ribosomes, rRNA processing, RNA splicing, and translation regulation & \cite{} \\ \hline
SNORD22 & Breast cancer & Up-regulation & p53 & Compromise tumorigenicity both in vitro and in vivo via activation of p53 & \cite{} \\ \hline
SNORD28 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD33 & Colorectal carcinoma & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD34 & Leukemia & Up-regulation & Unknown & Lead to the disorder of rRNA methylation, and also lead to the decrease of cell volume and the repair speed of damaged protein & \cite{} \\ \hline
SNORD35A & Leukemia & Up-regulation & Unknown & Lead to the disorder of rRNA methylation, and also lead to the decrease of cell volume and the repair speed of damaged protein & \cite{} \\ \hline
SNORD3A & Head and neck squamous cell carcinoma & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD3F & Head and neck squamous cell carcinoma & Up-regulation & Unknown & Be related to RNA editing & \cite{} \\ \hline
SNORD42A & Leukemia & Up-regulation & 20-O-methylation at Uridine 116 of 18S rRNA & An important snoRNA for the proliferation of leukemic cells & \cite{} \\ \hline
SNORD43 & Leukemia & Up-regulation & Unknown & Lead to the disorder of rRNA methylation, and also lead to the decrease of cell volume and the repair speed of damaged protein & \cite{} \\ \hline
SNORD44 & Colorectal carcinoma & Down-regulation & Caspase-dependent pathway, PI3K/Akt & Inhibit CRC cell proliferation and induced caspase-dependent cell apoptosis & \cite{} \\ \hline
nan & Gliomas & Down-regulation & "Caspase-
dependent
apoptosis pathway & " "Facilitate the apoptosis with
the inhibited proliferation,
invasion, and migration of
glioma cells & " \cite{} \\ \hline
nan & Prostate cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD46 & Breast cancer & Downregulation & Unknown & Unproved & \cite{} \\ \hline
SNORD46 & Sarcomas & Up-regulation & Unknown & Enrich in the regulation of gene expression, DNA replication, DNA repair, cell division, cell cycle, cell proliferation, oxidative phosphorylation, and response to drug & \cite{} \\ \hline
SNORD47 & Gliomas & Down-regulation & Unknown & Inhibit glioma cell growth, proliferation, colony formation, invasion, and migration, and induces G2-phase arrest in vivo and in vitro. & \cite{} \\ \hline
SNORD49A & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD50 & Colorectal carcinoma & Down-regulation & Methylation of C2848 in 28S rRNA & Unproved & \cite{} \\ \hline
SNORD50(A/B) & Breast cancer & Down-regulation & k-Ras & Downregulate mitosis-related genes, prolonged mitosis, repressed colony-forming ability, and clinical analyses & \cite{} \\ \hline
SNORD52 & Hepatocellular carcinoma & Up-regulation & CDK1 & Be associated with the poor prognosis of patients with HCC, acting as a functionally relevant snoRNA in HCC & \cite{} \\ \hline
SNORD55 & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD57 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD63 & Clear cell renal cell carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD66 & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD67 & Colorectal carcinoma & Up-regulation & Unknown & Be involved in systemic lupus erythematosus, alcoholism, viral carcinogenesis, transcriptional mis-regulation in cancer & \cite{} \\ \hline
SNORD73B & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD74 & Prostate cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD76 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Gliomas & Down-regulation & pRb & Arrest glioma cells at the S phase of the cell cycle, which in turn may affect the expression of cell cycle-associated proteins & \cite{} \\ \hline
nan & Hepatocellular carcinoma & Up-regulation & Wnt/b-catenin & Suppress cell proliferation by inducing G0/G1 cell cycle arrest and apoptosis & \cite{} \\ \hline
nan & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD78 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & "Head and neck
squamous cell
carcinoma & " Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Lung cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Prostate cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD81 & Prostate cancer & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD87 & Breast cancer & Up-regulation & p53 & Compromise tumorigenicity both in vitro and in vivo via activation of p53 & \cite{} \\ \hline
SNORD89 & Breast cancer & Down-regulation & Unknown & Unproved & \cite{} \\ \hline
nan & Ovarian cancer & Up-regulation & Notch1-c-Myc & Result in increased stemness markers, S phase cell cycle, cell proliferation, invasion, and migration ability in OV and CA cells & \cite{} \\ \hline
SNORD96A & Clear cell renal cell carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SNORD3A & Breast cancer & Up-regulation & p53 & Trigger a remarkably potent p53-dependent anti-tumor stress response involving the ribosomal proteins uL5 (RPL11) and uL18 (RPL5) & \cite{} \\ \hline
nan & Sarcomas & Down-regulation & Unknown & Enrich in oxidative phosphorylation, regulation of protein ubiquitination, cellular metabolic process, and RNA metabolic process & \cite{} \\ \hline
SNORD118/ SCARNA9L & Breast cancer & Up-regulation & p53 & Trigger a remarkably potent p53-dependent anti-tumor stress response involving the ribosomal proteins uL5 (RPL11) and uL18 (RPL5) & \cite{} \\ \hline
nan & Hepatocellular carcinoma & Up-regulation & Wnt/b-catenin & Inhibit the proliferation of HCC cells by inducing G0/G1 arrest and apoptosis & \cite{} \\ \hline
SCARNA6 & Leukemia & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SCARNA22 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
SCARNA15 & Colorectal carcinoma & Up-regulation & Unknown & Unproved & \cite{} \\ \hline
\end{longtable}
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